Nuclear Receptors as Drug Targets

Nuclear Receptors as Drug Targets

Eckhard Ottow (Editor), Hilmar Weinmann (Editor), Raimund Mannhold (Series Editor), Hugo Kubinyi (Series Editor), Gerd Folkers (Series Editor)
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G protein-coupled receptors (GPCRs) are one of the most important target classes in pharmacology and are the target of many blockbuster drugs. Yet only with the recent elucidation of the rhodopsin structure have these receptors become amenable to a rational drug design.

Based on recent examples from academia and the pharmaceutical industry, this book demonstrates how to apply the whole range of bioinformatics, chemoinformatics and molecular modeling tools to the rational design of novel drugs targeting GPCRs.

Essential reading for medicinal chemists and drug designers working with this largest class of drug targets in the human genome.

Kategorije:
Godina:
2008
Izdanje:
1
Izdavač:
Wiley-VCH
Jezik:
english
Strane:
522
ISBN 10:
3527318720
ISBN 13:
9783527318728
Serije:
Methods and Principles in Medicinal Chemistry (Book 39)
Fajl:
PDF, 4.40 MB
IPFS:
CID , CID Blake2b
english, 2008
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